IGF1R beta (phospho Tyr1135 / Tyr1136) / Insulin Receptor beta (phospho Tyr1150 / Tyr1151) antibody
官网链接
折扣/货期| 货号：GTX50154 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IGF1R beta (phospho Tyr1135 / Tyr1136) / Insulin Receptor beta (phospho Tyr1150 / Tyr1151) antibody
别名:
insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
靶标/特异性:
This antibody is raised against a synthetic peptide around phosphorylated Tyr1135 / Tyr1136 of IGF1R (signal peptide cleaved form), which is identical to the sequence around phosphorylated Tyr1150 / Tyr1151 of Insulin Receptor (signal peptide cleaved form of P06213-2).
同种型:
IgG
免疫原:
Peptide sequence around phosphorylation site of tyrosine 1135 / tyrosine 1136 (T-D-Y(p)-Y(p)-R-K) derived from human IGF1R.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
155
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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