IGF2R antibody-多抗-深圳欣博盛生物科技有限公司

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IGF2R antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX12397

规格：100μg

目录价：￥6300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IGF2R antibody

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ICC/IF, IHC-P, WB

同种型:

IgG

免疫原:

A synthetic peptide corresponding to a sequence at the C-terminus of human Mannose 6 Phosphate Receptor(Cation independent)(2475-2491aa TKLVSFHDDSDEDLLHI), different from the related rat and mouse sequences by one amino acid.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

500 μg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

274.38

产品形式:

Liquid

存储溶液:

0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA, 0.025% Thimerosal, 0.025% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

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