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折扣/货期| 货号：CHI-HF-21010RA-C050 | 规格：50 ug | 目录价：￥4620 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-10Ralpha (human):Fc (human) (rec.)
别名:
Interleukin-10 Receptor alpha; IL-10RA; CD210; IL-10R1; CDw210a;
产品描述:
CD210, also known as IL10RA, is a subunit for the interleukin-10 receptor. IL10RA has also been designated CDW210A (cluster of differentiation W210A). It is structurally related to interferon receptors. CD210 has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. It has been reported that CD210 promotes survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of CD210 leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
宿主来源:
HEK 293 cells
保存温度:
+4°C
运输温度:
BI
预期分子量:
~70-100kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Measured by its ability to inhibit IL-10-dependent proliferation of MC/9- 2 mouse mast cells.
内毒素水平:
<1EU/mg protein (LAL test; Lonza).
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