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折扣/货期| 货号：XP-5703-M | 规格：0.5 mg | 目录价：￥6598.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-4 Antibody [1.3_4F11-2G3]
别名:
Interleukin 4Interleukin-4, B-cell stimulatory factor 1, IL-4, BSF1, BCGF1, BSF-1, BCGF-1
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA,WB,Neutralization Assay
克隆性:
Monoclonal
克隆号:
1.3_4F11-2G3
纯化方式:
This IgG1k antibody was purified on a Protein A affinity column.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
IL-4 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚C when reconstituted.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Accession #:
P05112
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