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折扣/货期| 货号：40-744 | 规格：2 ug | 目录价：￥4071.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-6 Recombinant Protein (Animal Free)
别名:
26 kDa protein, IFN-β2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
表达系统:
E. coli
保存温度:
The recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.
纯度:
≥ 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to stimulate the proliferation of mouse 7TD1 cells. The expected ED50 is ≤ 0.02 ng/ml, corresponding to a specific activity of ≥ 5 x 107 units/mg.
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