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折扣/货期| 货号：GTX22105 | 规格：100μg | 目录价：￥4700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL1 beta antibody
别名:
interleukin 1 beta , IL-1 , IL1-BETA , IL1F2
反应种属:
Dog, Human
宿主来源:
Rabbit
实验应用:
ELISA, FCM, IHC-Fr, IHC-P, IP, Neutralizing/Inhibition, WB
靶标/特异性:
Primarily directed against mature 17kDa human IL-1beta. In ELISA formats and other immunoreactive assays, the antibody will recognize 10% of the non-denatured (native) 31kDa IL-1beta precursor containing samples, but will detect all of the 17kDa mature molecule. Also detects primate IL-1beta in the same formats using similar dilutions.The antiserum does not recognize human IL-1alpha.
同种型:
IgG
免疫原:
This antibody was prepared by repeated immunizations with recombinant human IL-1s produced in E.coli. The MW of the recombinant 153 aa IL-1s was 17 kDa with the N-terminal amino acid at position alanine 117. This cleavage site is generated by the IL-1s.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by DEAE chromatography.
偶联:
Unconjugated
产品浓度:
2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
31
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, no preservatives.
生产商:
GeneTex
功能与背景:
Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
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