| 货号:GTX27379 | 规格:50μg | 目录价:¥4300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IL10 antibody [JES5-2A5]
别名:
interleukin 10 , CSIF , Il-10
产品描述:
The JES5-2A5 antibody is specific for mouse IL-10. IL-10 has numerous biological activities including the ability to inhibit both the synthesis of Th1 cytokines and proliferation of T cells. In the mouse, IL-10 is produced by phagocytic cells, conventional dendritic, cells, T cells, B cells, and NK cells. The JES5-2A5 antibody is a neutralizing antibody.
反应种属:
Mouse
宿主来源:
Rat
实验应用:
ELISA, WB
同种型:
IgG2
免疫原:
This antibody was generated against the recombinant mouse IL-10 expressed in E. coli. It has not been reported to cross-react with rat IL-10.
克隆性:
Monoclonal
克隆号:
JES5-2A5
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]
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