官网链接
折扣/货期| 货号：GTX10778 | 规格：25μg | 目录价：￥6600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL10 Receptor beta antibody
别名:
interleukin 10 receptor subunit beta , CDW210B , CRF2-4 , CRFB4 , D21S58 , D21S66 , IL-10R2
反应种属:
Human
宿主来源:
Goat
实验应用:
ELISA, FCM, Neutralizing/Inhibition, WB
同种型:
IgG
免疫原:
Recombinant fragment (Human).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
37
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
Interleukin 10, initially named cytokine synthesis inhibitory factor (CSIF), is a potent immunosuppressant of macrophage functions. IL10, a pleiotropic cytokine, exerts either immunostimulatory or immunosuppressive effects on a number of cell types, including Thy2 cells, activated fetal thymocytes, macrophages, keratinocytes, and LY-1 (CD5+) and normal B cells. IL10 stimulates the growth of stem cells, mast cells, and thymocytes and also enhances cytotoxic T cell development, costimulates B cell differentiation, and immunoglobulin secretion. Interleukin 10 binds specifically and with high affinity to cell surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. Mouse and human cDNA clones encoding the ligand binding IL10 receptor have been isolated. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10. The human interleukin 10 receptor gene maps to chromosome 11q23.3.7
您可能感兴趣的产品
Tafazzin Polyclonal Antibody
货号：44967
HFE antibody
货号：GTX135988-S
DC-SIGN antibody
货号：GTX135602-S
SARS-CoV-2 (COVID-19) nsp3 antibody
货号：GTX135589-S
SARS-CoV-2 (COVID-19) nsp12 antibody
货号：GTX135467-S
SARS-CoV-2 (COVID-19) Nucleocapsid antibody
货号：GTX135357-S
CD81 antibody
货号：GTX135297-S
GCN2 antibody
货号：GTX135252-S
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询