IL12B / IL12 p40 antibody [MT86 + MT221]-单抗-深圳欣博盛生物科技有限公司

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IL12B / IL12 p40 antibody [MT86 + MT221]

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX02957

规格：250μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL12B / IL12 p40 antibody [MT86 + MT221]

别名:

CLMF,CLMF2,IL12B,IMD28,IMD29,NKSF,NKSF2,interleukin 12B,IL12 p40

反应种属:

Human, Monkey

宿主来源:

Mouse

实验应用:

ELISA, Sandwich ELISA

靶标/特异性:

This antibody is able to detect native and recombinant human p40 subunit of IL-12 and IL-23. In combination with MT704 for detection of IL-12 p70 heterodimer (p40 + p35), with MT618 for detection of IL-12/IL-23 (p40), and with MT155 for detection of IL-23 heterodimer (p40 + p19).

同种型:

IgG1

免疫原:

Recombinant human IL-23

克隆性:

Multiclonal

克隆号:

MT86 + MT221

纯化方式:

Protein G purified

偶联:

Unconjugated

产品浓度:

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]

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