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折扣/货期| 货号：GTX26104 | 规格：50μg | 目录价：￥2400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL1RAP blocking peptide
别名:
Interleukin 1 Receptor Accessory Protein , C3Orf13 , Il-1Racp , Il1R3 , Il1Rap
克隆号:
偶联:
Unconjugated
产品浓度:
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store the peptide at -20ºC, stable for one year.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAP). IL-1RAP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruits to the IL-1Rcomplex through IL-1RAP. IL-1 activation of stress activated protein kinase and of acid sphingomyelinase also requires IL-1RAP. Like IL-1RI, IL-1RAP subunit is essential for IL-1 mediated cellular response. IL-1RAP is expressed in many tissues.
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