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折扣/货期| 货号：GTX44232 | 规格：100μg | 目录价：￥6600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL2 Receptor alpha antibody [B1.49.9]
别名:
interleukin 2 receptor subunit alpha , CD25 , IDDM10 , IL2R , IMD41 , TCGFR , p55
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, IHC-Fr
靶标/特异性:
The molecular weight of the recognized antigen is 55kDa. The IL-2 receptor consists of at least three distinct membrane components: the alpha chain (IL-2R alpha, Tac, CD25), the beta chain (IL-2R beta, p75, CD122), and the gamma chain (IL-2R gamma). CD25 is undetectable on resting T cells but is induced upon T-cell activation. B1.49.9 recognizes activated T and B cells. CD25 is absent on thymocytes, resting T and B cells, and NK cells. B1.49.9 does not inhibit the in vitro IL2 dependent proliferation
同种型:
IgG2a
免疫原:
Human alloactivated T lymphocytes (FC2) kept in conditioned medium.
克隆性:
Monoclonal
克隆号:
B1.49.9
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, no preservatives.
生产商:
GeneTex
功能与背景:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
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