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折扣/货期| 货号：GTX13856 | 规格：200μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL21 Receptor antibody
别名:
interleukin 21 receptor , CD360 , IMD56 , NILR
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 65-80(CSLHRSAHNATHATYT) and 505-521 (CDFTSPGDEGPPRSYLR) of human IL-21R.
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
59
产品形式:
Liquid
存储溶液:
PBS, 0.2% Gelatin, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
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