IL21 Receptor antibody-多抗-深圳欣博盛生物科技有限公司

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IL21 Receptor antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX74411

规格：100μg

目录价：￥7200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL21 Receptor antibody

别名:

CD360 , IL21R , NILR , interleukin 21 receptor , IL21-R , IL21 Receptor

反应种属:

Human

宿主来源:

Rabbit

实验应用:

靶标/特异性:

This antibody recognizes an epitope at the N-terminus of human IL-21R.

同种型:

IgG

免疫原:

Peptide corresponding to aa 20-32 of human IL-21R precursor.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]

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