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IL6 Receptor antibody [B-R6]

品牌：GeneTex

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说明书

折扣/货期

货号：GTX76550

规格：100μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL6 Receptor antibody [B-R6]

别名:

interleukin 6 receptor , CD126 , IL-6R-1 , IL-6RA , IL6Q , IL6RA , IL6RQ , gp80

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, FCM, ICC/IF, IHC-Fr, IP

靶标/特异性:

This antibody recognizes human Interleukin-6 receptor subunit alpha and recognizes both the soluble and membranous human IL6 Receptor.

同种型:

IgG1

免疫原:

CHO cells transfected with cDNA of the IL-6 receptor.

克隆性:

Monoclonal

克隆号:

B-R6

纯化方式:

Purified by ion exchange chromatography

偶联:

Unconjugated

产品浓度:

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]

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