IL7 Receptor alpha antibody [A7R34] (FITC)-单抗-深圳欣博盛生物科技有限公司

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IL7 Receptor alpha antibody [A7R34] (FITC)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX01473-06

规格：100μg

目录价：￥2800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL7 Receptor alpha antibody [A7R34] (FITC)

别名:

interleukin 7 receptor , CD127 , IL-7Ralpha

产品描述:

The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).

反应种属:

Human, Mouse

宿主来源:

Rat

实验应用:

FCM

同种型:

IgG2a

克隆性:

Monoclonal

克隆号:

A7R34