官网链接
折扣/货期| 货号：GTX14374 | 规格：250μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ISG15 antibody
别名:
ISG15 ubiquitin like modifier , G1P2 , IFI15 , IMD38 , IP17 , UCRP , hUCRP
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, IHC, WB
同种型:
IgG
免疫原:
Recombinant human ISG15 protein.
克隆性:
Polyclonal
克隆号:
纯化方式:
IgG fraction
偶联:
Unconjugated
产品浓度:
5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
18
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
生产商:
GeneTex
功能与背景:
ISG15 a 15kDa homologue shows no amino acid sequence homology to cytokines and is synthesized as a precursor that is activated through processing by a thiol protease. ISG15 is secreted by monocytes and lymphocytes. Synthesis is induced in response to IFN alpha or IFN beta, but not IFN gamma. ISG15 expression is induced also by overexpression of some interferon regulatory factors that have been shown to play a role in the transcriptional regulation of IFN genes. ISG15 is secreted also by cell lines of monocyte (U937 cell line), T-lymphocyte, B-lymphocyte (DAUDI cells), human fibroblasts, and epithelial origins. The induction of terminal differentiation in human melanoma cells is associated, among other things, with alterations in the expression of ISG15. Intracellularly ISG15 has been shown to function as a ubiquitin homologue. It is known also as UCRP (ubiquitin cross-reactive protein). Serpin 2a (spi2a), a member of the serine protease inhibitor (serpin) protein family that is highly induced in macrophages during bacillus Calmette-Guerin infection has been shown to bind ISG15. ISG15 has been shown to modulate immune cell function. It possesses activities of cytokines and induces production of IFN gamma. It enhances proliferation and functions of natural killer and LAK cells.
您可能感兴趣的产品
Complement C3 antibody
货号：88R-7581
Rabbit Lambda light chain antibody (Prediluted for IHC)
货号：75R-1046
Rabbit Kappa light chain antibody (Prediluted for IHC)
货号：75R-1045
Streptococcus Group A antibody
货号：70-XR85
Trypsin antibody
货号：70-XR77S
Trypsin antibody
货号：70-XR77
TSH antibody
货号：70-XR75
Streptococcus Group A antibody
货号：70-XR73_R
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询