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折扣/货期| 货号：GTX70203 | 规格：100μl | 目录价：￥4300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Jab1 antibody [2A10.8]
别名:
COP9 signalosome subunit 5 , CSN5 , JAB1 , MOV-34 , SGN5
反应种属:
Drosophila, Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
ICC/IF, IHC, IP, WB
同种型:
IgG2b
免疫原:
The full-length mouse JAB-1 gene expressed in E. coli.
克隆性:
Monoclonal
克隆号:
2A10.8
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
38
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
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