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折扣/货期| 货号：GTX83031 | 规格：100μl | 目录价：￥6100 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
JNK3 antibody [10E4A4]
别名:
mitogen-activated protein kinase 10 , JNK3 , JNK3A , PRKM10 , SAPK1b , p493F12 , p54bSAPK
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, WB
同种型:
IgG1
免疫原:
Purified recombinant fragment of human JNK3 (aa28-233) expressed in E. Coli.
克隆性:
Monoclonal
克隆号:
10E4A4
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
53
产品形式:
Liquid
存储溶液:
Ascites, 0.03% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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