KIDINS220 antibody [C3], C-term-多抗-深圳欣博盛生物科技有限公司

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KIDINS220 antibody [C3], C-term

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX110503	规格：100μl	目录价：￥4000
货号：GTX110503-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

KIDINS220 antibody [C3], C-term

别名:

kinase D interacting substrate 220 , ARMS , SINO

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

IHC-P, WB

同种型:

IgG

免疫原:

Synthetic peptide encompassing a sequence within the Intracellular domain of human KIDINS220. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

197

产品形式:

Liquid

存储溶液:

0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

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