| 货号:GTX66843 | 规格:100μl | 目录价:¥6500 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Ku80 antibody [8H1]
别名:
X-ray repair cross complementing 5 , KARP-1 , KARP1 , KU80 , KUB2 , Ku86 , NFIV
反应种属:
Human, Monkey
宿主来源:
Mouse
实验应用:
ICC/IF, IP, WB
同种型:
IgG
免疫原:
Purified recombinant human XRCC5 protein fragments expressed in E.coli.
克隆性:
Monoclonal
克隆号:
8H1
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
83
产品形式:
Liquid
存储溶液:
100mM Tris-Glycine, 150mM NaCl, 50% Glycerol, 0.2% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
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