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折扣/货期| 货号：GTX66842 | 规格：100μl | 目录价：￥6500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BRG1 antibody [6D7]
别名:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , BAF190 , BAF190A , BRG1 , CSS4 , MRD16 , RTPS2 , SNF2 , SNF2L4 , SNF2LB , SWI2 , hSNF2b
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ICC/IF, IP, WB
同种型:
IgG
免疫原:
Purified recombinant human SMARCA4 protein fragments expressed in E.coli.
克隆性:
Monoclonal
克隆号:
6D7
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
185
产品形式:
Liquid
存储溶液:
100mM Tris-Glycine, 150mM NaCl, 50% Glycerol, 0.2% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
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