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折扣/货期| 货号：RF16080 | 规格：1 Set | 目录价：￥7590.375 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LAG3 Detection Set (Risk Free)
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA,WB,ICC,IHC-P,Flow,IF
同种型:
IgG1, IgG2a
克隆性:
Monoclonal
纯化方式:
Antibodies are supplied as protein A purified IgG1 and IgG2a.
偶联:
Unconjugated
产品浓度:
Antibody 1 mg/mL
保存温度:
Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1), negatively regulating T-cell function and homeostasis (2). It is expressed in B, T, and NK cells, monocytes, and dendritic cells (3), and acts to regulate T cell expansion (4). LAG3 is also an important immune checkpoint protein, with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions. Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1, suggesting that a dual antibody approach may prove useful in cancer immunotherapy.
ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein.
Validated for flow cytometry and ELISA
Rigorously tested for the following applications:
Immunoblot
Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Multiple antibodies per target allowing the user to choose the best antibody for their application
Available individually or as a set
Risk-FreeTM means they are guaranteed to work for their approved applications
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