TIGIT Detection Set (Risk Free)-其他-深圳欣博盛生物科技有限公司

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TIGIT Detection Set (Risk Free)

品牌：Prosci

官网链接

说明书

折扣/货期

货号：RF16050

规格：1 Set

目录价：￥7590.375

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TIGIT Detection Set (Risk Free)

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA,ICC,IHC-P,Flow,IF

同种型:

IgG1, IgG2a, IgG2b

克隆性:

Monoclonal

纯化方式:

Antibodies are supplied as protein A purified IgG2b.

偶联:

Unconjugated

产品浓度:

Antibody 1 mg/mL

保存温度:

Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. It is expressed on several classes of T cells including follicular B helper T cells (TFH). TIGIT has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses (1). Similar to other immune checkpoint proteins such as PD-1, TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer. Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer (2). ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

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