Lamin A + C antibody [JoL5]-单抗-深圳欣博盛生物科技有限公司

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Lamin A + C antibody [JoL5]

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX25090

规格：1ml

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Lamin A + C antibody [JoL5]

别名:

lamin A/C , CDCD1 , CDDC , CMD1A , CMT2B1 , EMD2 , FPL , FPLD , FPLD2 , HGPS , IDC , LDP1 , LFP , LGMD1B , LMN1 , LMNC , LMNL1 , MADA , PRO1

反应种属:

Human, Mouse

宿主来源:

Mouse

实验应用:

ICC/IF, WB

靶标/特异性:

Detects an un-phosphorylated form of lamin A/C and the epitope is mapped to the N-terminal head domain of both proteins. Works on human & mouse

同种型:

IgG2

免疫原:

Recombinant bacterially expressed human lamin A

克隆性:

Monoclonal

克隆号:

JoL5

纯化方式:

Unpurified

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

Tissue culture supernatant, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]

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