Laminin alpha 3A antibody [BG5]-单抗-深圳欣博盛生物科技有限公司

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Laminin alpha 3A antibody [BG5]

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX17685

规格：100μl

目录价：￥6800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Laminin alpha 3A antibody [BG5]

产品描述:

Laminins, which consist of three subunits called alpha, beta and gamma chains, are major cell-adhesive components of extracellular matrix, especially basement membranes (BMs). The laminin family is constituted of over 15 isoforms, and each member is expressed in a tissue-specific manner and plays a differential role in each tissue. In the case of laminin alpha 3 chain, there are two splicing variants, the truncated form alpha 3A and the full-length alpha 3B.. Laminin-3A32 (Lm3A32) , formerly called laminin-5 or -5A, is composed of alpha 3A, Beta 3 and gamma 2 chains and distributed in the skin, esophagus, lung, breast and other epithelial tissues. This antibody highly detects laiminin-3A32 in the basement membranes of normal epithelial tissues and of relatively benign or differentiated carcinomas. It may also detect laminin-3A11. As its sister clone F7 is specific for alpha 3B chain, the combination of BG5 and F7 is an important tool to investigate the difference of the full- length and truncated alpha 3 laminins. These antibodies, together with the anti-gamma 2 antibody P2H capable of detecting invasive cancers, are powerful tools in pathological analyses of human cancers.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, IHC-Fr, IHC-P, IP, Purification, WB

靶标/特异性:

This antibody specifically detects alpha 3A in IHC. However, this clone may cross react with alpha 3B in ELISA, IP and Western Blot.

同种型:

IgG2a

免疫原:

Recombinant human laminin-alpha 3B N-term ~190 kDa fragment. Alpha 3A chain is truncated form ,and alpha 3B chain is full length.

克隆性:

Monoclonal

克隆号:

BG5

纯化方式:

Unpurified

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

Ascites, no preservatives.

生产商:

GeneTex

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