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折扣/货期| 货号：GTX01915 | 规格：500μl | 目录价：￥10300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Langerin antibody [12D6]
别名:
CD207 molecule , CLEC4K
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
IgG2b
免疫原:
Prokaryotic recombinant protein of 29 kD corresponding to the external domain of the langerin molecule.
克隆性:
Monoclonal
克隆号:
12D6
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010]
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