LAP2 alpha antibody, C-term-多抗-深圳欣博盛生物科技有限公司

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LAP2 alpha antibody, C-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX80375

规格：50μl

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

LAP2 alpha antibody, C-term

别名:

Thymopoietin , Cmd1T , Lap2 , Lemd4 , Pro0868 , Tp , Tmpo

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ICC/IF, WB

靶标/特异性:

Reacts with human, rat & mouse LAP2α

同种型:

IgG

免疫原:

Recombinant LAP2α C terminus (amino acids 188-693)

克隆性:

Polyclonal

克隆号:

纯化方式:

Unpurified

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

Serum diluted with PBS, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A- type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eu karyotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, and MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. While LAP 2 beta binds to B-type lamins at the nuclear periphery and was suggested to regulate nuclear lamina growth , LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent/salt-resistant nucleoskeletal structure.

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