LDL receptor antibody-多抗-深圳欣博盛生物科技有限公司

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LDL receptor antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX14056

规格：50μg

目录价：￥7800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

LDL receptor antibody

别名:

low density lipoprotein receptor , FH , FHC , LDLCQ2

反应种属:

Human, Mouse, Rat

宿主来源:

Chicken

实验应用:

同种型:

IgY

免疫原:

Immunogen Sequence: GI # 4504975, sequence 29-205 Recombinant low density lipoprotein receptor

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

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