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折扣/货期| 货号：GTX12033 | 规格：50μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LEF1 antibody [1C3.1D10]
别名:
lymphoid enhancer binding factor 1 , LEF-1 , TCF10 , TCF1ALPHA , TCF7L3
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB
靶标/特异性:
Recognizes all human LEF1 isoforms using Western blotting. The antibody does not cross-react with TCF1 or TCF4.
同种型:
IgG1
免疫原:
Synthetic peptide: TGIPHPAIVT PQVKQEHPHT DSDLMHVKPQ HEQRKEQEPK RP, corresponding to amino acids 256-297 of Human LEF1.
克隆性:
Monoclonal
克隆号:
1C3.1D10
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.08% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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