官网链接
折扣/货期| 货号：90-528 | 规格：50 ug | 目录价：￥9477 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-27 Recombinant Protein
别名:
Interleukin-27
表达系统:
CHO cells
保存温度:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μl sterile water. Add 1X PBS to the desired protein concentration.
产地:
美国
生产商:
Prosci
功能与背景:
Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the IL-6/IL-12 family of long type I cytokines. It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23, and p28, the cloned 28 kDa glycoprotein that is related to the p35 chain of IL-12. IL-27 is expressed by monocytes, endothelial cells and dendritic cells. IL-27 binds to and signals through a heterodimeric receptor complex composed of WSX1 (TCCR) and gp130. Evidence suggests IL-27 interacts only with WSX-1. IL-27 has both anti- and proinflammatory properties. As an antiinflammatory, IL-27 seems to induce a general negative feedback program that limits T and NK-T cell activity. At the onset of infection, IL-27 induces an IL-12 receptor on naie CD4+ T cells, making them susceptible to subsequent IL-12 activity (and possible Th1 development). Notably, IL-12 family cytokines are both induced and inhibited by bacterial products. Microbes promote IL-27 secretion through TLR4, and also block IL-27 production via C5a induction.
纯度:
>98% (SDS-PAGE).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Accession #:
NP_005746/NP_663634
您可能感兴趣的产品
IL2 Recombinant Protein (e.coli Expressed)
货号：97-076
VEGF R2 Recombinant Protein
货号：97-070
EGF R Recombinant Protein
货号：97-063
EGF R Recombinant Protein
货号：97-062
M-CSF R Recombinant Protein
货号：97-015
M-CSF R Recombinant Protein
货号：97-014
IL-4 R alpha Recombinant Protein
货号：97-008
IL-4 R alpha Recombinant Protein
货号：97-007
促销活动
复制QQ号成功，请打开QQ后添加好友进行咨询