LIGHT Detection Set (Risk Free)-其他-深圳欣博盛生物科技有限公司

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LIGHT Detection Set (Risk Free)

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：RF16060

规格：1 Set

目录价：￥5104.125

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

LIGHT Detection Set (Risk Free)

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA,WB,ICC,IHC-P,Flow,IF

同种型:

IgG2b

克隆性:

Monoclonal

纯化方式:

Antibodies are supplied as protein A purified IgG2b.

偶联:

Unconjugated

产品浓度:

Antibody 1 mg/mL

保存温度:

Mouse Monoclonal: Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year.

As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

PBS containing 0.02% sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

LIGHT Antibody: LIGHT, also known as Tumor Necrosis Factor Superfamily member 14 (TNFSF14), is a co-stimulatory molecule that can regulate T-cell activation (1) and has recently been identified as an immune checkpoint protein. LIGHT binds to two different receptors, Herpes Virus Entry Mediator (HVEM) and Lymphotoxin beta Receptor (LTβR). While LIGHT binding to HVEM delivers a co-stimulatory signal to T cells (1), LIGHT binding to LTβR is critical for the formation of lymphoid structures which can stimulate T cell infiltration and activation of a tumor microenvironment, leading to rapid T cell-mediated tissue destruction (2). It has been shown that targeted delivery of LIGHT to tumors, thereby causing the T cell infiltration of the tumor, can enhance the response of the PD-1/PD-L1 checkpoint blockade anti-cancer therapy (3), suggesting that LIGHT may become a potent tool in anti-cancer treatment. ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

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