深圳欣博盛生物科技有限公司 a1

货号:GTX10561 规格:50μg 目录价:¥5300
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LIMK1 antibody
别名:
LIM domain kinase 1 , LIMK , LIMK-1
反应种属:
Mouse
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, WB
同种型:
IgG
免疫原:
Synthetic peptide corresponding to the C-terminal region near aa 620-647 of human LIM kinase protein.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
73
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
生产商:
GeneTex
功能与背景:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Two splice variant have been identified.
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