LIMP II antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

LIMP II antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85033

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

LIMP II antibody

别名:

scavenger receptor class B member 2 , AMRF , CD36L2 , EPM4 , HLGP85 , LGP85 , LIMP-2 , LIMPII , SR-BII

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

同种型:

IgG

免疫原:

LIMP2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human LIMP2.The immunogen is located within amino acids 70 - 120 of LIMP2.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The lysosomal integral membrane protein 2 (LIMP2) is a heavily glycosylated type III transmembrane protein, the majority of which exists in the lumen of the lysosome and a cytoplasmic domain of approximately 20 amino acids. A deficiency of LIMP2 in mice causes uretic pelvic junction obstruction, deafness, and peripheral neuropathy associated with impaired vesicular trafficking and distribution of apically expressed proteins. More recently, LIMP2 was shown to act as a receptor to bind b-glucocerebrosidase, the enzyme defective in Gaucher disease, a lysosomal storage disorder. LIMP2-deficient mice showed missorted as well as secreted b-glucocerebrosidase, suggesting that LIMP2 also functions as the mannose-6-phosphate-independent trafficking receptor. Despite its predicted molecular weight, LIMP2 runs at approximately 80 – 85 kDa in SDS-PAGE.

您可能感兴趣的产品

Anti-Cathepsin D

货号：01-12-030104-1mg

Tafazzin Polyclonal Antibody

SARS-CoV-2 (COVID-19) nsp3 antibody

货号：GTX135589-S

SARS-CoV-2 (COVID-19) nsp12 antibody