官网链接
折扣/货期| 货号：GTX121923 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX121923-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Lin28A antibody
别名:
lin-28 homolog A , CSDD1 , LIN-28 , LIN28 , ZCCHC1 , lin-28A
反应种属:
Human, Mouse, Pig
宿主来源:
Rabbit
实验应用:
FCM, ICC/IF, IHC-P, WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human Lin28A. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. In contrast, LIN28A down-regulation in neural stem cells by miR-125, allows the processing of pre-let-7. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation.
您可能感兴趣的产品
Lyve-1 (human) antibody
货号：RLT-102-PABI50
Anti-Collagenase (Clostridium histolyticum), polyclonal antibody from sheep
货号：NB-58050-01
Anti-Collagenase (Clostridium histolyticum) HRP, polyclonal antibody from sheep
货号：NB-58051-01
Kv1.3 antibody (PE)
货号：GTX16679-08
RPL22 antibody
货号：GTX130972
PCSK9 antibody
货号：GTX129859
Dab1 antibody [N1N3]
货号：GTX119336
6X His tag antibody
货号：GTX115045
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询