官网链接
折扣/货期| 货号：AG-40B-0182-3010 | 规格：3 x 10 ug | 目录价：￥6720 |
| 货号：AG-40B-0182-C010 | 规格：10 ug | 目录价：￥3360 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Lipoyl-TRIM21 (human) (rec.) (His)
别名:
E3 Ubiquitin-protein Ligase TRIM21; 52 kDa Ro Protein; Tripartite Motif-containing Protein 21
产品描述:
TRIM21 (tripartite motif-containing protein 21) is a cytosolic Fc receptor induced by interferon (IFN). TRIM21 is distinguished from other Fc receptors by showing broad antibody specificity as it can activate its functions upon binding to IgG, IgM as well as IgA while other Fc receptors display more restricted antibody isotype and subtype specificities. TRIM21 also functions as a E3 ligase. During infection, antibodies are delivered efficiently to the cytosol when bound to intracellular pathogens such as viruses and bacteria. The antibody-pathogen complex in the cytosol upon engagement of the protein TRIM21 is ubiquitinylated and degraded by the proteasome machinery. Trim-Away is a method to degrade endogenous proteins based on TRIM21, Fc receptor binding and ubiquitin ligase activity. TRIM21, which recognizes antibody-bound proteins of interest, targets them for degradation by the proteasome. The Lipoyl-TRIM21 (human) (His) (rec.) protein is used in the original papers describing Trim-Away.
宿主来源:
E. coli
产品浓度:
0.1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~68kDa
产品形式:
solid
存储溶液:
Lyophilized. Contains 50mM Tris-HCl, pH 8 and 300mM NaCl.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test).
您可能感兴趣的产品
Human Recombinant Alpha Synuclein (1-114) PFFs (C-terminal Truncated)
货号：SPR-537E
Human Recombinant Alpha Synuclein (1-114) PFFs (C-terminal Truncated)
货号：SPR-537C
Human Recombinant Alpha Synuclein (1-114) PFFs (C-terminal Truncated)
货号：SPR-537B
Human Recombinant Alpha Synuclein (1-114) Monomers (C-terminal Truncated)
货号：SPR-536E
Human Recombinant Alpha Synuclein (1-114) Monomers (C-terminal Truncated)
货号：SPR-536C
Human Recombinant Alpha Synuclein (1-114) Monomers (C-terminal Truncated)
货号：SPR-536B
Raptin (human, recombinant)
货号：45023-10 µg
Versican G1 Domain (human, recombinant)
货号：44299-20 µg
促销活动
精品推荐
相关产品推荐
IFN-gamma (mouse):Fc (silent) InVivoKine™
货号：AG-40B-0283-C050
NF-kB (p65) (human) (rec.) (His) (highly active)
货号：AG-40T-0020Y-C002
NF-kB (p50) (human) (rec.) (His) (highly active)
货号：AG-40T-0021Y-C002
DDB1/CRBN-Complex (human) (rec.) (untagged)
货号：SBB-SC0116-C025
DDB1 (human) (rec.) (His) (Avi) (Biotin)
货号：SBB-SC0140-C025
K48-linked Tri-Ubiquitin (human) (rec.) (untagged)
货号：SBB-UP0171-C025
复制QQ号成功，请打开QQ后添加好友进行咨询