VISTA [B7-H5] (human) (rec.) (His)-其他重组蛋白-深圳欣博盛生物科技有限公司

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VISTA [B7-H5] (human) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40B-0177-3010	规格：3 x 10 ug	目录价：￥3360
货号：AG-40B-0177-C010	规格：10 ug	目录价：￥1680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

VISTA [B7-H5] (human) (rec.) (His)

别名:

V-type Immunoglobulin Domain-containing Suppressor of T Cell Activation; Platelet Receptor Gi24; Stress-induced Secreted Protein-1; Sisp-1; V-set Domain-containing Immunoregulatory Receptor

产品描述:

Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with lower expression on CD4+ and CD8+ T cells. VISTA is a new negative checkpoint regulator that potently suppresses T cell activation. Overexpression of VISTA on tumors inhibits the protective anti-tumor immunity and blockade of VISTA enhances antitumor immunity in multiple tumor models. VISTA on antigen presenting cells (APC) delivers negative signaling to T cells via a yet-to-identify binding partner on T cells.

宿主来源:

HEK 293 cells

产品浓度:

0.1mg/ml after reconstitution

保存温度:

+4°C

运输温度:

预期分子量:

~30-40kDa (SDS-PAGE)

产品形式:

solid

存储溶液: