LY75/DEC-205 Antibody / CD205-单抗-深圳欣博盛生物科技有限公司

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LY75/DEC-205 Antibody / CD205

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9671SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

LY75/DEC-205 Antibody / CD205

产品描述:

DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multi-lectin receptor that belongs to the MMR (macrophage mannose receptor) family of multidomain molecules. MMR family molecules mediate membrane receptor targeting to endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products. Expressed in mature dendritic cells (DC), DEC-205 contains an extracellular N-terminal cysteine-rich domain, a fibronectin type II domain, ten C-type carbohydrate recognition domains, a single transmembrane region and a small cytoplasmic C-terminal domain (31 amino acids) containing a tyrosine at 1679. DEC-205 elicits either an agonistic or antagonistic effect on IL-4 function, which is demonstrated by the ability of DEC-205 to imitate IL-4-induced maturation of epithelium or to inhibit IL-4-induced proliferation of T cells, respectively. Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2b, kappa

免疫原:

A portion of amino acids 1006-1130 was used as the immunogen for the LY75/DEC-205 antibody.

克隆性:

Monoclonal (mouse origin)