深圳欣博盛生物科技有限公司 a1

MAFK antibody
货号:GTX129240-S 规格:25μl 目录价:¥1700
货号:GTX129240 规格:100μl 目录价:¥4000
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MAFK antibody
别名:
MAF bZIP transcription factor K , NFE2U , P18
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ChIP assay, IP, WB
同种型:
IgG
免疫原:
Full length human MAFK Recombinant protein.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
18
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM]
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