MAGI1 antibody-多抗-深圳欣博盛生物科技有限公司

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MAGI1 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX11473

规格：50μl

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MAGI1 antibody

别名:

membrane associated guanylate kinase, WW and PDZ domain containing 1 , AIP-3 , AIP3 , BAIAP1 , BAP-1 , BAP1 , MAGI-1 , MAGI-1b , Magi1d , TNRC19 , WWP3

反应种属:

Rat

宿主来源:

Rabbit

实验应用:

同种型:

IgG

免疫原:

synthetic peptide corresponding to amino acids 282-296 of MAGI-1 with a carboxy terminal added cysteine residue conjugated to maleimide-activated KLH. The sequence is conserved in human and mouse.

克隆性:

Polyclonal

克隆号:

纯化方式:

IgG fraction

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

IgG fraction, no preservatives.

生产商:

GeneTex

功能与背景:

The MAGUK (Membrane-Associated Guanylate Kinase) family of proteins is characterized by the presence of multi-PDZ and SH3 domains, and a single region of homology to Saccharomyces cerevisiae guanylate kinase (GuK) domain. All MAGUKs studied to date localize to regions of cell-cell contact such as tight junctions in epithelial cells and synaptic junctions in neurons and are believed to be involved in the assembly of multi-protein complexes via their protein-protein interaction domains. Three novel, closely related MAGUK proteins were isolated by means of different screening assays, and named MAGI1/BAP1, MAGI2/ S-SCAM /ARIP, and SLIPR/MAGI3. MAGI1 was first identified in mouse as a protein interacting with K-RasB. Three isoforms were identified, and named MAGI1a, MAGI1b, and MAGI1c, of 1139, 1171, and 1374 amino acids respectively. The isolation of a growing number of MAGI1 binding partners, together with the determination of the subcellular and tissue distribution of the different isoforms, are paving the way towards elucidation of its function.

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