MALT1 antibody [MT1/410]-单抗-深圳欣博盛生物科技有限公司

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MALT1 antibody [MT1/410]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX34812

规格：100μg

目录价：￥7000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MALT1 antibody [MT1/410]

别名:

IMD12 , MALT1 , MALT1 paracaspase , MLT , MLT1 , PCASP1

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P, WB

同种型:

IgG1

免疫原:

Human MALT1 recombinant fragment (aa701-808)

克隆性:

Monoclonal

克隆号:

MT1/410

纯化方式:

Protein A/G purified

偶联:

Unconjugated

产品浓度:

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.05% BSA, 0.05% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]

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