官网链接
折扣/货期| 货号：V7236SAF-100UG | 规格：100 ug | 目录价：￥6652.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MAML2 Antibody
产品描述:
Mastermind-like 2, also known as MAM2, MAM3 or MLLMAML2, is a nuclear speckle protein that acts as a transcriptional co-activator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAML2 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, it interacts with the ankyrin repeats of the Notch proteins (1-4). This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-Jκ; a complex that can then induce HES1 gene expression. While the N-terminal domain of MAML2 is essential for proper Notch binding, the C-terminal domain of MAML2 is essential for transcriptional activation. A chromosomal aberration involving the gene is implicated in mucoepidermoid carcinomas, clear cell hidradenomas and benign Warthin tumors.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
Mouse IgG2a, kappa
免疫原:
A human recombinant protein was used as the immunogen for this MAML2 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
MMLP2-1
纯化方式:
Protein G affinity chromatography
保存温度:
Store the MAML2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
您可能感兴趣的产品
KDM4A antibody [HL6181]
货号：GTX648273
C/EBP alpha antibody [HL6175]
货号：GTX648267
CD2AP antibody [HL6173]
货号：GTX648260
CD5 antibody [HL6108]
货号：GTX648193
PARP4 antibody [HL6034]
货号：GTX648108
IL2 Receptor alpha antibody [HL5991]
货号：GTX647605
ERG antibody [HL5975]
货号：GTX647589
Anillin antibody [HL5958]
货号：GTX647570
促销活动
复制QQ号成功，请打开QQ后添加好友进行咨询