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折扣/货期| 货号：GTX54445 | 规格：50μg | 目录价：￥5900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MASP1/3 antibody [2B11]
别名:
CRARF,CRARF1,MAP1,MASP,MASP1,MASP3,MAp44,PRSS5,RaRF,mannan binding lectin serine peptidase 1,3MC1
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IP, WB
靶标/特异性:
The antibody recognizes the heavy chain common to both MASP-1 and MASP-3.
同种型:
IgG1
克隆性:
Monoclonal
克隆号:
2B11
纯化方式:
Purified IgG1
偶联:
Unconjugated
产品浓度:
100 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
79
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, 0.1% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
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