MD2 antibody-多抗-深圳欣博盛生物科技有限公司

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MD2 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85517

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MD2 antibody

别名:

lymphocyte antigen 96 , ESOP-1 , MD-2 , MD2 , ly-96

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ELISA, IHC-Fr, IHC-P, WB

靶标/特异性:

This antibody is specific for MD-2 Internal

同种型:

IgG

免疫原:

MD-2 antibody was raised against a peptide corresponding to 13 amino acids near the center of human MD-2.The immunogen is located within the last 50 amino acids of MD-2.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS (5,6). The specificity of this response is determined by the species of MD-2; e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4 (7).

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