| 货号:GTX10379 | 规格:25μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MDC antibody
别名:
C-C motif chemokine ligand 22 , A-152E5.1 , ABCD-1 , DC/B-CK , MDC , SCYA22 , STCP-1
反应种属:
Human
宿主来源:
Chicken
实验应用:
ELISA, WB
靶标/特异性:
The antibody shows 20% cross-reactivity with recombinant human MPIF-1, 10% cross-reactivity with recombinant human MIP-1δ and 1% cross-reactivity with recombinant mouse MDC, human HCC-1, human I-309, mouse MIP-1α, viral MIP-I, mouse MIP-1β and mouse MIP-1γ.
同种型:
IgY
免疫原:
recombinant human MDC expressed in E. coli.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
11
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
MDC is a member of the beta (CC) chemokine family and induces chemotaxis or calcium mobilization in dendritic cells, IL-2 activated cells and activated T lymphocytes. MDC, also named stimulated T cell chemotactic protein (STCP-1), was isolated from clones of monocyted-derived macrophages and binds to CC chemokine receptor 4 (CCR4). MDC shows less than 35% identity to other C-C chemokine family members. It is expressed in dendritic cells, macrophages and activated monocytes. Expression is also detected in the tissues of thymus, lymph node and appendix. NH2- terminally truncated forms of natural MDC were isolated from a CD8+ T cell clone and have been reported to inhibit HIV-1 infection.
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