官网链接
折扣/货期| 货号：GTX48728 | 规格：50μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MDM2 antibody
别名:
transformed mouse 3T3 cell double minute 2 , 1700007J15Rik , AA415488 , Mdm-2
反应种属:
Mouse
宿主来源:
Rabbit
实验应用:
ELISA, IP, WB
同种型:
IgG
免疫原:
Synthetic peptide corresponding to an internal region near aa 175-200 of mouse MDM2.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
55
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
生产商:
GeneTex
功能与背景:
MDM2 is a nuclear phosphoprotein with an apparent molecular mass of 90 kD that forms a complex with the p53 tumor suppressor protein. Human MDM2 was identified as a homologous product of the 'murine double minute 2' gene (mdm2). The MDM2 gene enhances the tumorigenic potential of cells when it is overexpressed and encodes a putative transcription factor. Forming a tight complex with the p53 gene, the MDM2 oncogene can inhibit p53-mediated transactivation. MDM2 binds to p53 and amplification of MDM2 in sarcomas leads to escape from p53-regulated growth control. This mechanism of tumorigenesis parallels that for virus-induced tumors in which viral oncogene products bind to and functionally inactivate p53.Over-expression of the
您可能感兴趣的产品
Tafazzin Polyclonal Antibody
货号：44967
HFE antibody
货号：GTX135988-S
DC-SIGN antibody
货号：GTX135602-S
SARS-CoV-2 (COVID-19) nsp3 antibody
货号：GTX135589-S
SARS-CoV-2 (COVID-19) nsp12 antibody
货号：GTX135467-S
SARS-CoV-2 (COVID-19) Nucleocapsid antibody
货号：GTX135357-S
CD81 antibody
货号：GTX135297-S
GCN2 antibody
货号：GTX135252-S
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询