| 货号:V9704SAF-100UG | 规格:100 ug | 目录价:¥6414.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MEF2D Antibody
产品描述:
The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF4, are one class of identified factors. A second family of DNA-binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
反应种属:
Human
宿主来源:
Mouse
实验应用:
FACS, IF, IHC-P
同种型:
Mouse IgG2b
免疫原:
Recombinant full-length human MEF2D protein was used as the immunogen for the MEF2D antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-MEF2D-3A4
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the MEF2D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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