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折扣/货期| 货号：GTX20731 | 规格：500μl | 目录价：￥6600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Melan A antibody [DT101 + BC199]
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
IHC-Fr, IHC-P
靶标/特异性:
This antibody recognizes a protein of 18kDa, identified at Melan A (Melanoma Antigen Recognized by T- cells 1) or Melan-A. The MART-1 recognizes a subcellular fraction found in melanosomes. The antibody labels melanomas and tumors showing melanocytic differentiation. It does not mark neoplasms of epithelial origin, lymphomas or mesenchymal tumors. Melan-A is a useful addition to melanoma panels as it is apparently specific for melanocytic lesions. Both HMB-45 and MART-1 are coexpressed in the majority of melanomas, as well as uniquely expressed in certain cases. Studies have shown that MART-1 is more sensitive than HMB-45 when labeling metastatic melanomas.
同种型:
IgG
免疫原:
Recombinant full length protein (Human).
克隆性:
Multiclonal
克隆号:
DT101 + BC199
偶联:
Unconjugated
产品浓度:
10 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant diluted with PBS, protein carrier, Proprietary preservative , not Sodium azide or Thimerosal.
生产商:
GeneTex
功能与背景:
MART-1 (Melanoma Antigen Recognized by T cells) or Melan-A is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.
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