MIF Antibody / Macrophage Migration Inhibitory Factor-单抗-深圳欣博盛生物科技有限公司

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MIF Antibody / Macrophage Migration Inhibitory Factor

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9662SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

MIF Antibody / Macrophage Migration Inhibitory Factor

产品描述:

Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor (GIF), is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, IHC-P

同种型:

Mouse IgG2a, kappa

免疫原:

A recombinant fragment from the human protein was used as the immunogen for the MIF antibody.

克隆性:

Monoclonal (mouse origin)