MIP1 beta antibody-多抗-深圳欣博盛生物科技有限公司

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MIP1 beta antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX10383

规格：25μg

目录价：￥6600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MIP1 beta antibody

别名:

C-C motif chemokine ligand 4 , ACT2 , AT744.1 , G-26 , HC21 , LAG-1 , LAG1 , MIP-1-beta , MIP1B , MIP1B1 , SCYA2 , SCYA4

反应种属:

Human

宿主来源:

Goat

实验应用:

ELISA, IHC-Fr, Neutralizing/Inhibition, WB

同种型:

IgG

免疫原:

Purified insect cell line Sf21-derived recombinant human MIP-1beta.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, no preservatives.

生产商:

GeneTex

功能与背景:

MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD-5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.

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