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折扣/货期| 货号：GTX03352 | 规格：100μl | 目录价：￥5900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MLCK (phospho Tyr464) antibody
别名:
myosin light chain kinase , AAT7 , KRP , MLCK , MLCK1 , MLCK108 , MLCK210 , MSTP083 , MYLK1 , smMLCK
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, WB
同种型:
IgG
免疫原:
A synthesized peptide derived from Human MYLK(Accession Q15746), corresponding to amino acid residues L449-L474.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
211
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
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